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His idea was this: when given in normal (allopathic) dosage, a drug (in the sense of medicament) will produce a constellation of symptoms; however, in a patient whose disease symptoms resemble just this mosaic of symptoms, the same drug (simile principle) would effect a cure when given in a very low dosage (“potentiation”).
Change in Elimination Characteristics During Drug Therapy (B) With any drug taken regularly and accumulating to the desired plasma level, it is important to consider that conditions for biotransformation and excretion do not necessarily remain constant. Elimination may be hastened due to enzyme induction or to a change in urinary pH. |
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