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Without exception, however, prompt action is imperative. Thus, a staggered treatment schedule has proven useful. The antiplatelet agent, ASA, is administered at the first suspected signs of infarction. Pain due to ischemia is treated predominantly with antianginal drugs (e. g. , nitrates).
Meanwhile, ACh is hydrolyzed by acetylcholinesterase (p. 100); excitation of the endplate subsides. If no AP follows, Ca2+ is taken up again by the SR and the myofilaments relax. Clinically important drugs (with the exception of dantrolene) all interfere with neural control of the muscle cell. |
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